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      • IN LONG COVID
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      • IN PARKINSON'S DISEASE
      • IN LEWY BODY DEMENTIA
      • IN MULTIPLE SCLEROSIS
      • IN DIABETES
      • IN LUPUS ERYTHEMATOSUS
      • IN SPINAL CORD INJURY
      • IN ARTHRITIS & PAIN
      • IN MIGRAINE & DEPRESSION
      • INFLAMMATION & INSOMNIA
    • WEBINARS
      • WEBINAR GALLERY
      • THE BIOLOGY OF AGING
      • ALZHEIMER'S DISEASE
      • PARKINSON'S DISEASE
      • DEPRESSION
      • FRONTOTEMPORAL DEMENTIAS
      • MULTIPLE SYSTEM ATROPHY
    • CONTACT US
  • HOME
  • ABOUT US
    • ABOUT THE COMPANY
    • THE TEAM
    • CHIEF EXECUTIVE OFFICER
    • CHIEF PHYSICIAN ADVISOR
    • CLINICAL NEUROSCIENCE
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  • FORZA™
    • ABOUT FORZA™
    • THE STORY
    • THE SOURCE
    • THE PLAN
    • CALORIE RESTRICTION
    • VIRTUAL LIBRARY
  • REVIEWS
    • THE REVIEWS
    • IN LONG COVID
    • IN ALZHEIMER'S DISEASE
    • IN PARKINSON'S DISEASE
    • IN LEWY BODY DEMENTIA
    • IN MULTIPLE SCLEROSIS
    • IN DIABETES
    • IN LUPUS ERYTHEMATOSUS
    • IN SPINAL CORD INJURY
    • IN ARTHRITIS & PAIN
    • IN MIGRAINE & DEPRESSION
    • INFLAMMATION & INSOMNIA
  • WEBINARS
    • WEBINAR GALLERY
    • THE BIOLOGY OF AGING
    • ALZHEIMER'S DISEASE
    • PARKINSON'S DISEASE
    • DEPRESSION
    • FRONTOTEMPORAL DEMENTIAS
    • MULTIPLE SYSTEM ATROPHY
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VIRTUAL LIBRARY


A SELECTION OF RELEVANT SCIENTIFIC PULBICATIONS

ADIPONECTIN & OSMOTIN

INDEPENDENT R&D

This page offers a comprehensive selection of relevant scientific, peer-reviewed publications describing the function of the key human hormone Adiponectin and that of its plant counterpart - the powerful protein Osmotin.

ADIPONECTIN - THE KEY LIFESPAN REGULATOR

Follow the links below to read key international published research on Adiponectin - the key life-span regulator - and its receptors:

  • Adiponectin and Adiponectin Receptors


  • Adiponectin/adiponectin receptor in disease and aging


  • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome 


THE OSMOTIN-ADIPONECTIN CONNECTION

OSMOTIN AS A PLANT THERAPEUTIC PROTEIN

Click on the links below to learn about Osmotin's therapeutic activity:

  • Novel phytopeptide osmotin mimics preventive effects of adiponectin on vascular inflammation and atherosclerosis.


  • The Adiponectin Homolog Osmotin Enhances Neurite Outgrowth and Synaptic Complexity via AdipoR1/NgR1 Signaling in Alzheimer's Disease.


  • Osmotin-loaded magnetic nanoparticles with electromagnetic guidance for the treatment of Alzheimer's disease. 


  • Osmotin attenuates amyloid beta- induced memory impairment, tau phosphorylation and neurodegeneration in the mouse  hippocampus


  • Novel osmotin inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer’s disease neuropathological deficits


  • Neuroprotective effect of osmotin against ethanol-induced apoptotic neurodegeneration in the developing rat brain


  • Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain  


  • Adiponectin and Plant-Derived Mammalian Adiponectin Homolog Exert a Protective Effect in Murine Colitis   

A-C

Adiponectin - key adipokine in Metabolic Syndrome (pdf)

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Adiponectin - the past two decades (pdf)

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Adiponectin - Therapeutic Target for Obesity Diabetes and EC Dysfx (pdf)

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Adiponectin = A Potential Therapeutic Target in AD and Obesity (pdf)

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Adiponectin and Its Mimics (pdf)

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Adiponectin and its receptor in disease and aging (pdf)

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Adiponectin Centric Dietary Intervention to Improve COVID19 (pdf)

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Adiponectin Receptor in Healthy Longevity and Obesity (pdf)

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Adiponectin Receptor in Healthy Longevity (pdf)

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Adiponectin Receptor Signaling - New layer (pdf)

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Adiponectin Signalling in the CNS (pdf)

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ADPNr Signaling in the Brain (pdf)

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COVID long term risks for AD (pdf)

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COVID19 and CNS microvascular injury and neuroINFLAM (pdf)

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CRM and Age Related Diseases - Targets MOA Rx Potential (pdf)

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C-P

Cytokines, Sickness Behavior and Depression (pdf)

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Immunometabolic actions of ADPN (pdf)

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Mol Psych - Osmotin promotes alpha secretase via SIRT and AMPK (pdf)

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mTOR pathways (pdf)

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mTOR Signaling in Growth Control and Disease (pdf)

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mTOR Signaling in Growth, Metabolism, Disease (pdf)

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Multifaceted Physiological Roles of Adiponectin in INFLAM and disease (pdf)

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NatureMedicine_2019 - INFLAM Across the Lifecycle (pdf)

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Neuroprotective effect of osmotin against ETOH induced Neurodegeneration (pdf)

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Osmotin - a plant sentinel and agonist of adiponectin (pdf)

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Osmotin and Atherosclerosis (pdf)

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Osmotin attenuates LPS-induced neuro-inflammation (pdf)

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Osmotin attenuates LPS-induced. INFLAM and AD Biomarkers (pdf)

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Overview of CR Mimetics (pdf)

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PPAR-Nnat-NF-kB Axis Mediates Effects of AdPN on Adipocytes (pdf)

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P-T

PPARa Target Genes and Effects (pdf)

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Reduced ADPN in COVID Critical Illness (pdf)

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review of adiponectin biology in INFLAM and CI (pdf)

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Role of Adiponectin in Central Nervous System Disorders (pdf)

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Statin Impact on APN Levels (pdf)

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Tissue Specific Effects of ADPN (pdf)

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CONTACT US

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

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